1668-S2 AMH MACE CLOD 169

2SHB 1668 - H AMD 1092

By Representative MacEwen

On page 1, beginning on line 10, after "that" strike "may be impairing" and insert "are class A cannabinoids"

On page 1, line 16, after "for any" strike "impairing cannabinoid" and insert "class A cannabinoid"

On page 2, beginning on line 2, after "regulate all" strike "cannabinoids that may be impairing" and insert "class A cannabinoids"

On page 3, at the beginning of line 20, strike "cannabinoid that may be impairing" and insert "class A cannabinoid"

On page 3, line 21, after "(i)" insert "" "Class A cannabinoid" means a substance that meets the following structural and functional criteria:

(1) The substance exhibits the structural backbone of tetrahydrocannabinols and tetrahydrocannabinol-like (THC-like) molecules that include the interconnected three-ring system of a: Six-carbon aromatic ring; pyran ring; and cyclohexene/cyclohexane ring. Known compounds that fit the description in this subsection (i)(1) include:

(i) Tetrahydrocannabinols – a single double-bond in the C ring:

(A) Delta-10-THC and isomers;

(B) Delta-9-THC and isomers;

(C) Delta-8-THC and isomers;

(D) Delta-7-THC and isomers;

(E) Delta-6a-THC and isomers; and

(F) Delta-10a-THC and isomers;

(ii) Hexahydrocannabinol – no double bonds in the C ring;

(iii) Carboxylates (C-2 and C-4) of tetrahydrocannabinols or hexahydrocannabinol:

(A) Delta-9-THC acid (Delta-9-THCA);

(B) Similar carboxylates of Delta-9-THCA for tetrahydrocannabinols in (1)(i)(A) through (F) of this subsection (i); and

(C) Carboxylate esters in (1)(i)(A) through (F) of this subsection (i);

(iv) Alkyl analogues (C-3) of tetrahydrocannabinols or hexahydrocannabinol:

(A) Delta-9-THCP (Delta-9-tetrahydrocannabiphorol) and n-alkyl analogues;

(B) Similar alkylated analogues of Delta-9-THC for tetrahydrocannabinols in (1)(i)(A) through (F) of this subsection (i); and

(v) Hydroxylated analogues of tetrahydrocannabinols or hexahydrocannabinol:

(A) 11-hydroxy-delta-9-THC and 8- and 10-hydroxy analogues; and

(B) Similar hydroxylated analogues of Delta-9-THC for tetrahydrocannabinols in (1)(i)(A) through (F) of this subsection (i);

(2) Possesses significant CB1 agonist activity as demonstrable by binding affinity (Ki) to the CB1 receptors at less than 200 nM; and

(3) Results in positive effects for all four components of the tetrad test in rodents or reliably causes functional impairment in humans as assayed by a method possessing scientific consensus.

(j) "Class B cannabinoid" means all cannabinoids that do not meet the form and function of class A cannabinoids.

(k)"

Reletter the remaining subsections consecutively and correct any internal references accordingly.

On page 5, beginning on line 29, after "(aa)" strike all material through "(bb)" on line 35

Reletter the remaining subsections consecutively and correct any internal references accordingly.

On page 7, at the beginning of line 33, strike "cannabinoid that may be impairing" and insert "class A cannabinoid"

On page 11, beginning on line 32, after "of a" strike "cannabinoid that may be impairing" and insert "class A cannabinoid"

On page 11, beginning on line 37, after "marketed as" strike "having impairing effects" and insert "a class A cannabinoid"

On page 12, line 13, after "containing" strike "cannabinoids that may be impairing" and insert "class A cannabinoids"

On page 12, at the beginning of line 18, strike "cannabinoid that may be impairing" and insert "class A cannabinoid"

On page 13, at the beginning of line 23, strike "cannabinoid that may be impairing" and insert "class A cannabinoid"

On page 14, line 4, after "of a" strike "cannabinoid that may be impairing" and insert "class A cannabinoid"

On page 15, beginning on line 27, after "other" strike "nonimpairing cannabinoids" and insert "class B cannabinoids"

On page 15, line 28, after "cannabinoids, or" strike "nonimpairing" and insert "class B cannabinoid"

On page 15, at the beginning of line 30, strike "nonimpairing cannabinoid" and insert "class B cannabinoid"

On page 15, line 38, after "((cannabidiol))" strike "nonimpairing cannabinoid" and insert "class B cannabinoid"

On page 16, line 2, after "or other" strike "nonimpairing cannabinoid" and insert "class B cannabinoid"

On page 16, line 4, after "other" strike "nonimpairing cannabinoid" and insert "class B cannabinoid"

On page 16, at the beginning of line 7, strike "cannabinoid that may be impairing" and insert "class A cannabinoid"

On page 16, line 18, after "substance that" strike "may be impairing" and insert "is a class A cannabinoid"

On page 16, line 24, after "or other" strike "nonimpairing cannabinoid" and insert "class B cannabinoid"

On page 16, line 36, after "other" strike "nonimpairing cannabinoid" and insert "class B cannabinoid"

On page 20, at the beginning of line 9, strike "cannabinoids that may be impairing" and insert "class A cannabinoids"

On page 26, after line 5, insert the following:

"NEW SECTION. Sec. 13. A new section is added to chapter 69.50 RCW to read as follows:

Class A cannabinoids may not be sold in the general market, except naturally occurring hemp delta-9-THC and THCA at or below 0.3 percent with marketed and labeled class B cannabinoids present."

Renumber the remaining sections consecutively and correct any internal references accordingly.

Correct the title.

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